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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

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Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Access Research Resources

Recent Publications

Life-course socioeconomic position and the gut microbiome in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Batalha MA, LeCroy MN, Lin J, Peters BA, Qi Q, Wang Z, Wang T, Gallo LC, Talavera GA, McClain AC, Thyagarajan B, Daviglus ML, Hou L, Llabre M, Cai J, Kaplan RC, Isasi CR.

Gut Microbes. 2025 Dec;17(1):2479772. doi: 10.1080/19490976.2025.2479772. Epub 2025 Mar 18.

Melanoma and Matrimony: Retrospective Study of Demographics, Marital Status, and Clinical Features of Patients With Acral Melanoma at a Single Academic Center.

Albucker SJ, Desai AD, Falotico JM, Magro C, Mancebo S, Lipner SR.

Pigment Cell Melanoma Res. 2025 May;38(3):e70019. doi: 10.1111/pcmr.70019.

Cadmium exposure induces Leydig cell injury via necroptosis caused by oxidative stress and TNF-α/TNFR1 signaling.

Zheng X, Sun Y, Wang J, Yin Y, Li Z, Liu B, Hu H, Xu J, Dai Y, Kanwar YS, Tang Y.

Biochem Biophys Res Commun. 2025 May 1;761:151717. doi: 10.1016/j.bbrc.2025.151717. Epub 2025 Mar 31.

A multidimensional tool for quantifying structural racism: Application to adverse pregnancy outcomes in Chicago, Illinois.

Freedman AA, Keenan-Devlin LS, Smart BP, Odom-Konja RM, Gallivan SU, Franklin AD, Crockett AH, Ernst LM, Borders A, Miller GE.

Soc Sci Med. 2025 May;372:118013. doi: 10.1016/j.socscimed.2025.118013. Epub 2025 Mar 21.

Clinicopathologic analysis and digital pathology evaluation of orchiectomy specimens in gender-affirmation surgery.

Riva-Morales I, Gama A, Zhou R, Choy B, Isaila B, Nezami BG, Brannigan R, Bowen D, Yang X.

Pathol Res Pract. 2025 May;269:155914. doi: 10.1016/j.prp.2025.155914. Epub 2025 Mar 13.

Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation and cell cycle progression.

Shannon N, Raymond C, Palmer C, Homa S, Bonini M, Seward D, Cunniff B.

J Cell Sci. 2025 May 1;138(9):jcs263554. doi: 10.1242/jcs.263554. Epub 2025 Apr 2.

Assessment of Liver Fibrosis Through Shear Wave Elastography in Pediatric Liver Transplant Recipients.

Ravanbakhsh N, Ro E, Melin-Aldana H, Chen W, Mohammad S, Benya EC, Kaj-Carbaidwala B, Whitehead B, Alonso EM, Chapin CA, Kriegermeier A.

Pediatr Transplant. 2025 May;29(3):e70056. doi: 10.1111/petr.70056.

Spatial transcriptomics of Glomerulo-centric antibody mediated rejection in renal transplants.

Margeta D, Noguchi H, Khazaie S, Herlitz LC, Augustine JJ, Heeger PS, Tambur AR, Fairchild RL, Baldwin WM 3rd.

Clin Immunol. 2025 May;274:110460. doi: 10.1016/j.clim.2025.110460. Epub 2025 Feb 22.

PIM kinase inhibition counters resistance to radiotherapy and chemotherapy in human prostate cancer.

Rajkumar-Calkins A, Sagar V, Wang J, Bailey S, Anderson P, Abdulkadir SA, Kirschner AN.

Radiother Oncol. 2025 May;206:110794. doi: 10.1016/j.radonc.2025.110794. Epub 2025 Feb 18.

Reply by Authors.

Tosoian JJ, Zhang Y, Meyers JI, Heaton S, Siddiqui J, Xiao L, Assani KD, Barocas DA, Ross AE, Chopra Z, Herron GC, Edelson JA, Graham NJ, Singhal U, Salami SS, Morgan TM, Palapattu GS, Wei JT, Chinnaiyan AM.

J Urol. 2025 May;213(5):589. doi: 10.1097/JU.0000000000004450. Epub 2025 Feb 7.

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