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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

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Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Access Research Resources

Recent Publications

Evidence-Based Surgical Guidelines for Treating Children With Rhabdomyosarcoma.

Abdelhafeez AH, Reljic T, Klocksieben F, Kumar A, Cox S, Davidoff AM, Munanzvi K, van Scheltinga CEJST, Elgendy A, Gerstle JT, Qureshi B, Nasir A, Lautz TB, Moreno AA, Loh A, Qureshi S, Vujanić GM, Lobos P, Mukkada S, Abib S.

Pediatr Blood Cancer. 2025 Apr;72(4):e31541. doi: 10.1002/pbc.31541. Epub 2025 Jan 27.

Individualized transfusion decisions to minimize adverse cardiovascular outcomes in patients with acute myocardial infarction and anemia.

Portela GT, Ducrocq G, Bertolet M, Alexander JH, Goodman SG, Glynn S, Strom JB, Swanson SA, Lemesle G, Rao SV, Tessalee M, Polonsky TS, Goldfarb M, Traverse JH, Uhl L, Herbert BM, Silvain J, Carson JL, Brooks MM; MINT Trial Investigators.

Am Heart J. 2025 Apr;282:146-155. doi: 10.1016/j.ahj.2025.01.009. Epub 2025 Jan 17.

The fuzzy MAD stroke conjecture, using Fuzzy C Means to classify multimodal apparent diffusion for ischemic stroke lesion stratification.

Damen FC, Su C, Tsuruda J, Anderson T, Valyi-Nagy T, Li W, Shaghaghi M, Jiang R, Xie C, Cai K.

Magn Reson Imaging. 2025 Apr;117:110294. doi: 10.1016/j.mri.2024.110294. Epub 2024 Dec 4.

Unveiling the resistance risk and resistance mechanism of florylpicoxamid in Corynespora cassiicola from cucumber.

Peng Q, Hao X, Liu C, Li X, Lu X, Liu X.

Pestic Biochem Physiol. 2025 Mar;208:106228. doi: 10.1016/j.pestbp.2024.106228. Epub 2024 Dec 2.

NNFit: A Self-Supervised Deep Learning Method for Accelerated Quantification of High-Resolution Short-Echo-Time MR Spectroscopy Datasets.

Giuffrida AS, Sheriff S, Huang V, Weinberg BD, Cooper LAD, Liu Y, Soher BJ, Treadway M, Maudsley AA, Shim H.

Radiol Artif Intell. 2025 Mar;7(2):e230579. doi: 10.1148/ryai.230579.

Rhabdoid Tumor of the Kidney and Soft Tissues: Results from National Wilms Tumor Study-5 and Children's Oncology Group Study AREN0321.

Geller JI, Renfro LA, Grundy PE, Perlman EJ, Kalapurakal JA, Ehrlich PF, Biegel J, Huff V, Warwick AB, Paulino A, Mullen EA, Daw NC, Hoffer FA, Tochner Z, Gow K, Gratias E, Ward DA, Anderson JR, Fernandez CV, Dome JS.

Pediatr Blood Cancer. 2025 Mar;72(3):e31490. doi: 10.1002/pbc.31490. Epub 2024 Dec 19.

Heterogeneity in response to neoadjuvant radiotherapy between soft tissue sarcoma histotypes: associations between radiology and pathology findings.

Gennaro N, van der Loo I, Reijers SJM, van Boven H, Snaebjornsson P, Bekers EM, Bodalal Z, Trebeschi S, Schrage YM, van der Graaf WTA, van Houdt WJ, Haas RLM, Velichko YS, Beets-Tan RGH, Bruining A.

Eur Radiol. 2025 Mar;35(3):1337-1350. doi: 10.1007/s00330-024-11258-6. Epub 2024 Dec 19.

Treatment of Critical Bleeds in Patients With Immune Thrombocytopenia: A Systematic Review.

Chowdhury SR, Sirotich E, Guyatt G, Gill D, Modi D, Venier LM, Mahamad S, Chowdhury MR, Eisa K, Beck CE, Breakey VR, de Wit K, Porter S, Webert KE, Cuker A, O'Connor C, -DiRaimo JM, Yan JW, Manski C, Kelton JG, Kang M, Strachan G, Hassan Z, Pruitt B, Pai M, Grace RF, Paynter D, Charness J, Cooper N, Fein S, Agarwal A, Nazaryan H, Siddiqui I, Leong R, Pallapothu S, Wen A, Xu E, Liu B, Shafiee A, Rathod P, Kwon H, Dookie J, Zeraatkar D, Thabane L, Couban R, Arnold DM.

Eur J Haematol. 2025 Mar;114(3):458-468. doi: 10.1111/ejh.14351. Epub 2024 Nov 18.

Infectious Morbidity and All-cause Mortality of Infants HIV-exposed Uninfected Compared to Infants HIV-unexposed Uninfected in Botswana.

Dubois MM, Jao J, Sun S, Legbedze J, Schenkel S, Mmasa N, Kgole SW, Masasa G, Happel AU, Iwase SC, Haghighat R, Moyo S, Sharma TS, Edlefsen PT, Shao D, Jaspan H, Powis KM.

Pediatr Infect Dis J. 2025 Mar 1;44(3):214-216. doi: 10.1097/INF.0000000000004603. Epub 2024 Oct 31.

Pumping the Breaks on Acantholytic Skin Disorders: Targeting Calcium Pumps, Desmosomes, and Downstream Signaling in Darier, Hailey-Hailey, and Grover Disease.

Harmon RM, Ayers JL, McCarthy EF, Kowalczyk AP, Green KJ, Simpson CL.

J Invest Dermatol. 2025 Mar;145(3):494-508. doi: 10.1016/j.jid.2024.06.1289. Epub 2024 Aug 29.

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